Abstract #3272
Correction for T1 effects on MRI estimation of muscle sodium levels
Ping Wang 1 , Isaac V Manzanera Esteve 1 , Charles Nockowski 2 , and John C Gore 1
1
Vanderbilt University Institute of Imaging
Science, Nashville, TN, United States,
2
Philips
Healthcare Technical Support at Vanderbilt, Nashville,
TN, United States
The effects of T1 on estimates of sodium content in
human muscle have been evaluated. Our data confirm that
sodium levels estimated by comparing MRI signals to
calibration phantoms are inaccurate unless the
relaxation times of the tissue and phantom match, or
unless longer TR values are used so that both tissue and
phantom are fully relaxed. When simple solutions of
sodium are used as references standards, if TR is
greater than 130ms, the relative error in the reported
tissue sodium content is reduced to < 5%.
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