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Abstract #3297

Local Electrical Properties Tomography With Global Regularization By Gradient

Jiaen Liu 1 , Xiaotong Zhang 1 , Yicun Wang 1 , Pierre-Francois Van de Moortele 2 , and Bin He 1,3

1 Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota, United States, 2 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, United States, 3 Institute for Engineering in Medicine, University of Minnesota, Minneapolis, Minnesota, United States

The in vivo electrical conductivity and permittivity of tissues at Larmor frequency carries important information for both diagnostic purpose and real-time subject-specific local SAR quantification. Traditional electrical properties tomography (EPT) derives a local solution and can be severely deteriorated due to noise contamination. In the present study, a new approach was proposed to improve the local EPT solution with global regularization by the spatial gradient information of electrical properties, which is deducted from measured transmit B1 field induced in a multi-channel radiofrequency coil. Experiments involving a controlled physical phantom and healthy human subject were conducted to evaluate the proposed algorithm.

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