Slice multiplexed chemical exchange saturation transfer

CEST acquisition is usually limited to single slice as different frequency saturations are played out which may interfere with adjacent slices. On the other hand, certain applications call for the need of a larger spatial coverage in slice direction due to the heterogeneity of the region of interest. An example could be glioma, which may be associated with edema that responses differently in APT measurement from the tumor. In this work, a slice multiplexed CEST acquisition is proposed, in which two or more slices that experience the same CEST saturation are simultaneously acquired.

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