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Abstract #3343

A robust method to estimate CEST MRI parametric maps in vivo: Simultaneous quantification of concentration and exchange rate by minimizing the Lp norm

Julio Crdenas-Rodrguez 1 and Mark D. Pagel 1

1 Biomedical Engineering, University of Arizona, Tucson, AZ, United States

We have designed a new curve fitting method for CEST data using the L1/2 and L1 norms. This methods overcomes the limitations of standard least square curve fitting algorithm, and makes it feasible to obtain robust and quantitative estimates of CEST paramaters in vivo.

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