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Abstract #3347

Matrix-Algebra-Based Modeling Approach to MT, NOE and CEST for an Arbitrary Number of Interacting Spin Pools

Tobias Lenich 1 , Andr Pampel 1 , and Harald E. Mller 1

1 Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany

We introduce an efficient modeling and simulation method, capable of simulating MR experiments for arbitrary many spin pools. It is based on a matrix-algebra based calculation of the Bloch-McConnell equations for n spin pools, including the effects of cross-relaxation (nuclear Overhauser effect (NOE)), chemical exchange saturation transfer (CEST) and magnetization transfer involving a macromolecular pool (MT) on MR experiments.

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