Abstract #3349
In vitro study of CEST effects from endogenous metabolites at 3 T and 7 T
Jae-Seung Lee 1,2 , Ding Xia 1 , Alexej Jerschow 2 , and Ravinder R. Regatte 1
1
Department of Radiology, New York
University, New York, NY, United States,
2
Department
of Chemistry, New York University, New York, NY, United
States
In biological tissues and organs, many endogenous CEST
agents coexist, and their CEST effects often overlap.
Characterizing individual CEST effects from different
metabolites would be useful for interpreting such
overlapped CEST effects and for designing new CEST
applications. Here we performed an
in
vitro
study
to evaluate individual CEST effects arising from common
metabolites found in biological tissues and organs. The
CEST effects of those common metabolites were compared
between 3 T and 7 T, in consideration of the exchange
regime and the acidity of the exchangeable protons.
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