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Abstract #3390

Three-Dimensional MR Fingerprinting (MRF) and MRF-Music Acquisitions

Dan Ma 1 , Eric Y Pierre 1 , Yun Jiang 1 , Kawin Setsompop 2 , Vikas Gulani 3 , and Mark A Griswold 3

1 Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2 A.A Martinos Center for Biomedical Engineering, MGH, Harvard Medical School, Boston, MA, United States, 3 Radiology, Case Western Reserve University, Cleveland, OH, United States

The purpose of this study is to extend the 2D MR Fingerprinting (MRF) and MRF-Music framework to 3D acquisitions. Both methods were originally implemented in 2D acquisitions and have shown high scan efficiency for quantifying multiple tissue properties simultaneously. In addition to the multi-parameter quantification in MRF, the MRF-Music sequence was proposed to provide musical sounds that can dramatically improve the patients experience in the MR scanner. In this study, the MRF and MRF-Music sequences were implemented to achieve 3D coverage while still maintaining a high scan efficiency and providing desirable sounds. T1 and T2 values from phantom studies of the 3D slab selective MRF and MRF-Music methods showed good agreement to the values from the standard measurements. The T1, T2, off-resonance and M0 maps from 3D non-selective MRF and MRF-Music also showed promising results of achieving 3D isotropic quantitative mapping.

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