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Abstract #3391

PET-MRF: One-step 6-minute multi-parametric PET-MR imaging using MR fingerprinting and multi-modality joint image reconstruction

Florian Knoll 1,2 , Martijn A Cloos 1,2 , Thomas Koesters 1,2 , Michael Zenge 3 , Ricardo Otazo 1,2 , and Daniel K Sodickson 1,2

1 Center for Advanced Imaging Innovation and Research (CAI2R), NYU School of Medicine, New York, NY, United States, 2 Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, NYU School of Medicine, New York, NY, United States, 3 Siemens Medical Solutions USA, Malvern, PA, United States

Despite the extensive opportunities offered by PET-MR systems, their use is still far from routine clinical practice. While it is feasible to acquire PET data in about 5 minutes, collecting the clinically relevant variety of traditional MR contrasts requires substantially more time. This bottleneck formed by the traditional MR paradigm leads to inefficient use of the PET component. This work proposes a one-step procedure that merges the MR fingerprinting framework with the PET acquisition, and employs a dedicated multi-modality reconstruction to enable a 6 minute comprehensive PET-MR exam, which can provide the majority of clinical MR contrasts alongside quantitative parametric maps of the relaxation parameters (T1,T2) together with improved PET images.

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