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Abstract #3443

A longitudinal resting state functional MRI study of children with hemiplegic cerebral palsy treated with constraint therapy

Kathryn Yvonne Manning 1 , Darcy Fehlings 2 , Ronit Mesterman 3 , Jan Willem Gorter 4 , Lauren Switzer 2 , Craig Campbell 5 , and Ravi S. Menon 6

1 Medical Biophysics, University of Western Ontario, London, Ontario, Canada, 2 Department of Paediatrics, Holland Bloorview Kids Rehabilitation Hospital, Toronto, Ontario, Canada, 3 CanChild Centre for Childhood Disability Research, McMaster Children's Hospital, Hamilton, Ontario, Canada, 4 CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, Ontario, Canada, 5 Department of Paediatrics, University of Western Ontario, London, Ontario, Canada, 6 Centre for Functional and Metabolic Mapping, University of Western Ontario, London, Ontario, Canada

A longitudinal resting state functional MRI study of children with hemiplegic cerebral palsy treated with constraint therapy. Children with unilateral sensorimotor connectivity patterns tend to improve the most, and networks become more balanced after therapy while control subjects remained unchanged.

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