Abstract #3467
Birth weight influence white matter development in neonates: a diffusion tensor study based on tract-based spatial statistics
Yanyan Li 1 , Xianjun Li 1,2 , Jie Gao 1 , Qinli Sun 1 , Huan Li 1 , and Jian Yang 1,2
1
Department of radiology, the first
affiliated hospital of medical college, Xi'an Jiaotong
University, Xi'an, Shaanxi, China,
2
Department
of Biomedical Engineering, School of Life Science and
Technology, Xi' an Jiaotong University, Xi'an, Shaanxi,
China
No studies have specifically investigated that if the
birth weight as an independent index would influence the
white matter development in neonates. This diffusion
tensor study demonstrated that increment of birth weight
is related to significant increase of FA and decrease of
MD and RD in projection fibers (internal capsule and
corona radiata), commissural fibers (corpus callosum)
and association tracts (arcuate fasciculus) by using the
tract-based spatial statistics with postmenstrual age as
a covariate. The results demonstrated that the birth
weight as an independent factor exerted the positive
effects on neonatal white matter development.
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