Abstract #3500
A Comparison of MP-RAGE Sequence Optimizations
Jinghua Wang 1 , Lili He 2 , and Zhong-Lin Lu 1
1
Center for Cognitive and Behavioral Brain
Imaging, The Ohio State University, Columbus, Ohio,
United States,
2
Center
for Perinatal Research, The Research Institute at
Nationwide Children's Hospital, Ohio, United States
Magnetization-prepared rapid gradient echo sequence has
been widely used for classifying brain tissues in voxel-based
morphometry, detecting pathological changes of the
brain, estimating regional brain volume abnormalities,
assessing brain development, and evaluating treatment or
therapeutic responses. Over years, many attempts have
been made to optimize the sequence to improve image
quality with whole brain coverage in shorter scan time.
In this study, we evaluate the signal-to-noise ratio and
GM-WM contrast-to-noise ratio acquired using four
different sets of optimized parameters recommended by
different institutes.
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