Fluid-Attenuated Three-Dimensional Structural Brain MRI Using Inversion-Recovery-Prepared DANTE-FLASH (IR-DASH)

DANTE pulse trains can be used to suppress moving blood signal with minimal impact to the static tissue signal. We introduce an inversion recovery prepared 3D DANTE-FLASH (denoted as IR-DASH) that is able to generate 1 mm isotropic resolution full brain images with attenuated fluids (arterial blood and CSF) signal and comparable CNR(WM/GM) to conventional MP-RAGE images. The preliminary results showed that segmentation of grey matter could be significantly improved due to the blood suppression of DANTE pulse trains compared with conventional MP-RAGE brain structure images.

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