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Abstract #3523

White Matter Abnormalities in Alcohol Dependents using Diffusion Tensor Imaging at 3T

Hyeon-Man Baek 1,2 , Mirim Bang 1 , Youngjae Jeon 1 , and Jooyun Kim 1

1 Center for MR Research, Korea Basic Science Institute, Ochang, Chungbuk, Korea, 2 Department of Bio-Analytical Science, Univerity of Science & Technology, Daejeon, Chungnam, Korea

We applied quantitative DTI to investigate the association between alcohol use and white matter integrity in adults. The purpose of this study was to examine the reproducibility of the DTI by evaluating measures of anisotropy and diffusivity in brain regions such as the fornix, cingulum, and the corpus callosum. In the FA map of alcoholic, the white matter in the area of cingulum and corpus callosum shows a decrease in fractional anisotropy.

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