Abstract #3562
Lower Glutathione Levels in the Anterior Cingulate Cortex of Patients with Schizophrenia: A preliminary 3T 1H-MRS Study
Napapon Sailasuta 1 , Yusuke Iwata 1 , Shinichiro Nakajima 1 , Sofia Chavez 1 , Fernando Caravaggio 1 , Eric Plitman 1 , Vincenzo De Luca 1 , Jun Ku Chung 1 , Philip Gerretsen 1 , Gary Remington 1 , and Ariel Graff-Guerrero 1
1
The Centre for Addiction and Mental Health,
toronto, ON, Canada
Our current stuty is aimed to compare Glutathione (GSH)
levels between in patients with Schizophrenia (Sz) and
healty controls (HC) quantified in the ACC employing a
validated J-editing quantification method.GSH levels
were quantified with 1H-MRS. Our pilot data demonstrated
lower levels of GSH/H2O in ACC in patients with Sz
compared with HC (P= 0.0002).
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
