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Abstract #3580

Middle cerebral artery plaques in recent small subcortical infarction on 3D High-resolution black blood MRI at 3.0T

Lei Zhang 1 , Jianping Jia 2 , Yiu-Cho Chung 1 , Qi Yang 3 , Xin Liu 1 , Ying Han 2 , and Xiaodong Zou 2

1 Paul C. Lauterbur Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academic of Sciences, Shenzhen, Guangdong, China, 2 Neurology, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China, 3 Radiology, Xuanwu Hospital, Capital Medical University, Beijing, Beijing, China

Single subcortical infarction (SSI) in middle cerebral artery (MCA) territory has been considered to be mainly caused by lipohyalinosis or atherosclerosis. We investigated the presence of MCA plaques in patients with SSI using three-dimensional (3D) high-resolution black-blood MRI imaging, and found that atherosclerosis was more prevalent than commonly thought among patients with SSI. Meanwhile, Ipsilateral MCA had higher frequencies of atherosclerotic than contralateral side, most of which were superiorly located. 3D HR-MRI can noninvasively in vivo providing detailed information of intracranial atherosclerotic plaques with broad coverage in approximately 6 min and could strengthen our comprehension of SSI mechanism.

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