Abstract #3581
Aberrant regional homogeneity related to cognitive impairment in subcortical stroke patients: A resting-state fMRI study
Cheng-Yu Peng 1 , Ying Cui 1 , Deng-Ling Zhao 1 , Yun Jiao 1 , Shenghong Ju 1 , and Gao-Jun Teng 1
1
Jiangsu Key Laboratory of Molecular and
Functional Imaging, Department of Radiology, Zhongda
Hospita, Nanjing, Jiangsu, China
A stroke can increase the risk of vascular cognitive
impairment. This study utilised resting-state fMRI to
investigate regional homogeneity (ReHo) changes in
subcortical stroke patients and whether these changes
were correlated with cognitive performance. The stroke
patients exhibited significant deficiencies in relevant
cognitive domains and also demonstrated significantly
aberrant ReHo values in some specific brain regions
compared with the healthy controls. Moreover, the ReHo
values of the right superior temporal gyrus/middle
temporal gyrus were significantly correlated with the
cognitive test scores in the stroke group. ReHo could
represent a promising tool for the observation of
neurobiological consequences in post-stroke patients.
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