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Abstract #3657

Addressing phase errors in quantitative water-fat imaging at 3 T using a time-interleaved multi-echo gradient-echo acquisition

Stefan Ruschke 1 , Holger Eggers 2 , Hendrik Kooijman 3 , Thomas Baum 1 , Marcus Settles 1 , Axel Haase 4 , Ernst J. Rummeny 1 , and Dimitrios C. Karampinos 1

1 Department of Diagnostic and Interventional Radiology, Technische Universitt Mnchen, Munich, Bayern, Germany, 2 Philips Research, Hamburg, Hamburg, Germany, 3 Philips Healthcare, Hamburg, Hamburg, Germany, 4 Zentralinstitut fr Medizintechnik, Technische Universitt Mnchen, Garching, Bayern, Germany

Phase errors are known to cause significant bias in fat fraction estimation using complex-based water-fat separation. Time-interleaved multi-echo gradient-echo (TIMGE) acquisitions (where echoes are time interleaved and acquired in multiple TRs) are highly desirable at 3 T, as they enable high spatial resolution while maintaining short echo time steps. However, their phase error behavior has not been previously addressed. The present study aims to decompose the phase errors in TIMGE and propose a methodology to correct for the effect of phase errors in TIMGE acquisitions.

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