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Abstract #3659

An Efficient Chemical-shift Encoded Imaging for Liver Fat Quantification

Abraam S Soliman 1,2 and Charles A McKenzie 1,3

1 Biomedical Engineering, University of Western Ontario, London, Ontario, Canada, 2 Robarts Research Institute, Imaging Research Laboratories, London, Ontario, Canada, 3 Medical Biophysics, University of Western Ontario, London, Ontario, Canada

Chemical-shift encoded-water fat imaging is usually performed using multi-gradient-echo sequence. Unipolar echoes are acquired over multiple TR in order to achieve optimal echo-spacing. Although bipolar acquisitions are more efficient than the unipolar ones, they suffer from phase and magnitude errors that disrupt the fat quantification process. We have recently proposed a new bipolar sequence that can overcome these errors and provide accurate fat measurement. In this work we demonstrate the efficiency of this sequence for whole liver imaging, commonly used for the diagnosis of non-alcoholic fatty liver disease (NAFLD).

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