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Abstract #3677

A Novel Profile/View Ordering (NINJA-STAR) for High-Resolution 3D Volumetric T1 Mapping

Sui-Cheng Wang 1,2 , Amit R. Patel 2 , Akiko Tanaka 3 , Hui Wang 4 , Xiang Zhu 5 , Dianwen Zhang 6 , Takeyoshi Ota 3 , Roberto M. Lang 2 , and Keigo Kawaji 2

1 Biomedical Engineering, Northwestern University, Evanston, Illinois, United States, 2 Medicine, Section of Cardiology, The University of Chicago, Chicago, Illinois, United States, 3 Surgery, The University of Chicago, Chicago, Illinois, United States, 4 Philips Medical Systems, Cleveland, Ohio, United States, 5 College of Information and Electrical Engineering, and College of Economics & Management, China Agricultural University, Beijing, China, 6 Imaging Technology group, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States

Myocardial T1 mapping, which is used to detect diffuse fibrosis and quantify extracellular volumes, often employs 8-10 mm 2D slice acquisitions. However, this approach may be unsuited for accurate quantification of small tissues samples. 3D T1 mapping is desirable, and a FAN-type view ordering has recently been shown to improve through-plane resolution over multiple breath-holds. In this study, we propose a new view order method called NINJA-STAR (or NJS), which allows efficiently acquisition of 3D MRI k-space in a reduced number of breath-holds, and examine this approach in both phantom experiments and in-vivo.

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