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Abstract #3705

The comprehensive contrast-enhanced neuro exam

R. Marc Lebel 1,2 , Yi Guo 3 , Yinghua Zhu 3 , Sajan Goud Lingala 3 , Richard Frayne 2 , Linda B Andersen 2 , Jacob Easaw 4 , and Krishna S Nayak 3

1 GE Healthcare, Calgary, Alberta, Canada, 2 Radiology, University of Calgary, Calgary, Alberta, Canada, 3 Electrical Engineering, University of Southern California, Los Angeles, California, United States, 4 Oncology, University of Calgary, Calgary, Alberta, Canada

We describe the use of sparse data sampling and constrained iterative reconstruction to provide a comprehensive contrast-enhanced brain exam. Data acquisition is performed with a 3D Cartesian radial trajectory that is amenable to retrospective definition of the temporal resolution. Multiple image reconstructions are performed to obtain all salient pieces of information desired from a contrast enhanced brain exam. We demonstrate that pre- and post-contrast anatomical T1-weighted images, dynamic angiography, quantitative permeability mapping, and quantitative perfusion mapping can all be achieved simultaneously - with high spatial resolution and full brain coverage.

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