High resolution T1 mapping within seconds: model-based reconstruction without regularization

In this work we present a model-based reconstruction algorithm for the reconstruction of high resolution T1 maps from a fast spoiler-gradient free radial IR-FLASH sequence. By using minimal TR and formulating the problem in the parameter domain, no further regularization techniques are necessary. The resulting non-linear optimization problem is solved by the Gauss-Newton method. A phantom study revealed good agreement of the T1 values with the gold standard and a first in vivo experiment using the same parameter set as in the phantom study proofed the proposed technique to be robust.

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