Abstract #3755
Human thalamic structure segmentation with universal SHape Interpolation using the Radon Transform (uSHIRT)
Peter Adany 1 , In-Young Choi 1,2 , Erica Sherry 1 , and Phil Lee 1,3
1
Hoglund Brain Imaging Center, University of
Kansas Medical Center, Kansas City, KS, United States,
2
Neurology,
University of Kansas Medical Center, Kansas City, KS,
United States,
3
Molecular
and Integrative Physiology, University of Kansas Medical
Center, Kansas City, KS, United States
Despite the functional importance of the thalamus
including the regulation of consciousness, sleep and
alertness, its structural analysis is challenging,
requiring significant manual segmentation with
cumbersome editing of 3D shapes as 2D contours. The
currently available interpolation tools (linear, sinc,
trilinear, etc.) present an obstacle because they do not
create smooth contours, i.e., the interpolation is based
on the intensity rather than a shape of the target
structure. Our proposed universal Shape Interpolation
using the Radon Transform (uSHIRT) presents an
advancement from currently available analysis methods,
as it greatly improves and facilitates coregistration,
reslicing and editing masks in different planes.
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