Abstract #3842
Development of a Screening MRI Protocol for the Detection of Prostate Cancer: Initial Experience
Shivani Pahwa 1 , Robert Abouassaly 2 , Yun Jiang 3 , Karin Herrmann 4,5 , Raj Paspulati 5,6 , William Tabayoyong 7 , Soham Shah 7 , Brian Minnillo 7 , Gregory MacLennan 7 , Mark Griswold 1,8 , Lee Ponsky 5,9 , and Vikas Gulani 5,10
1
Radiology, Case Western Reserve University,
Cleveland, Ohio, United States,
2
University
Hospitals, Ohio, United States,
3
Biomedical
Engineering, Case Western Reserve University, Cleveland,
Ohio, United States,
4
Radiology,
University Hospitals, Ohio, United States,
5
CWRU
School of Medicine, Ohio, United States,
6
UH
Case Medical Center, Ohio, United States,
7
Urology,
University Hospitals, Ohio, United States,
8
Biomedical
Engineering, Case Western Reserve University, Ohio,
United States,
9
Urology,
UH Case Medical Center, Ohio, United States,
10
Radiology,
UH Case Medical Center, Ohio, United States
Serum PSA measurement and digital rectal examination
(DRE) are the current standards of care for detection of
prostate cancer. However, the performance of these
methods as screening tools has been criticized because
they over diagnose a large number of patients with
clinically insignificant disease, adding to a
significant morbidity for the patient without improving
the outcome. We propose a novel, short non-contrast
imaging protocol as a secondary screening tool that
helps direct targeted biopsies on suspicious lesions.
Our preliminary experience indicated that this strategy
increases the accuracy of detecting clinically
significant disease, and improves risk stratification
for biopsy.
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