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Abstract #3849

Evaluation of the diagnostic differentiation of prostate cancer from benign prostate hyperplasia using Intra-voxel incoherent motion MR imaging

Meiyu Sun 1 , Ailian Liu 1 , Ye Li 1 , Lihua Chen 1 , Qingwei Song 1 , Bin Xu 1 , and Ziheng Zhang 2

1 the first affiliated hospital of Dalian Medical University, Dalian, Liaoning, China, 2 GE healthcare China, Beijing, China

The MR imaging of prostate cancer (PCa) was undistinguishable from that of benign prostatic hyperplasia (BPH) on conventional T2WI and dynamic contrast enhancement imaging. In this study, intravoxel incoherent motion (IVIM) DWI were performed to investigate the diffusion and perfusion features of PCa and BPH, and to evaluate the relationship of the parameters, standard ADC, slow ADC, fast ADC and fraction of fast ADC, as well as their sensitivity and specificity in diagnosis. It was demonstrated standard ADC and slow ADC from IVIM MRI maybe a significant MRI biomarkers to differentiate PCa from BPH with satisfying sensitivity and specificity.

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