Abstract #3849
Evaluation of the diagnostic differentiation of prostate cancer from benign prostate hyperplasia using Intra-voxel incoherent motion MR imaging
Meiyu Sun 1 , Ailian Liu 1 , Ye Li 1 , Lihua Chen 1 , Qingwei Song 1 , Bin Xu 1 , and Ziheng Zhang 2
1
the first affiliated hospital of Dalian
Medical University, Dalian, Liaoning, China,
2
GE
healthcare China, Beijing, China
The MR imaging of prostate cancer (PCa) was
undistinguishable from that of benign prostatic
hyperplasia (BPH) on conventional T2WI and dynamic
contrast enhancement imaging. In this study, intravoxel
incoherent motion (IVIM) DWI were performed to
investigate the diffusion and perfusion features of PCa
and BPH, and to evaluate the relationship of the
parameters, standard ADC, slow ADC, fast ADC and
fraction of fast ADC, as well as their sensitivity and
specificity in diagnosis. It was demonstrated standard
ADC and slow ADC from IVIM MRI maybe a significant MRI
biomarkers to differentiate PCa from BPH with satisfying
sensitivity and specificity.
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