Abstract #3865
DCE-MRI Assessment of Soft-Tissue Sarcoma Response to Preoperative Therapy
Wei Huang 1 , Megan L Holtorf 1 , Aneela Afzal 1 , Yiyi Chen 1 , Brooke R Beckett 1 , and Christopher W Ryan 1
1
Oregon Health & Science University,
Portland, OR, United States
Twenty patients with extremity soft-tissue sarcoma who
underwent preoperative chemoradiotherapy consented to
research DCE-MRI, performed before, after one cycle of
chemotherapy, and after completion of therapy before
surgery. Ktrans and kep at baseline, after one cycle of
therapy, and percent change were much better than RECIST
tumor size measurement for early prediction of therapy
response. Post-therapy Ktrans, ve, and kep were
negatively correlated with necrosis percentage (NP) of
the surgical specimen. No significant relationship was
observed between post-therapy RECIST and NP.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
