Using UTE images for bone/air segmentation: applications for radiation therapy

Accurate bone segmentation is essential for the generation of (i) electron density maps needed for dose calculation in MR-only radiotherapy treatment planning (RTP) and (ii) MR-based attenuation correction maps in hybrid PET/MRI systems. While UTE sequences improve the visualization of tissues with short T2 such as cortical bone (1), efficient and robust segmentation of bone and air remains a significant challenge (2). To address this need, we introduce an application that uses a novel hybrid magnitude and phase UTE approach to differentiate tissue types, facilitate accurate segmentation, and generate synthetic CTs (synCTs) for the brain.

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