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Abstract #3879

Clinical Evaluation of TWIST DIXON Sequence with Flexible View Sharing for Breast DCE MRI: Can Initial Uptake Phase Provide Accurate Diagnosis

Yuan Le 1 , Hal D Kipfer 1 , Shadie S Majidi 1 , Brian Dale 2 , Marcel Dominik Nickel 3 , Randall Kroeker 2 , Elisabeth Weiland 3 , and Chen Lin 1

1 Radiology and Imaging Science, Indiana University School of Medicine, Indianapolis, IN, United States, 2 Siemens Medical Solutions, NC, United States, 3 Siemens Healthcare, Erlangen, Bavaria, Germany

A modified Time-resolved angiography With Stochastic Trajectories (TWIST) sequence with flexible view sharing and dual-echo DIXON was evaluated in clinical breast DCE-MRI for its capability of measuring initial uptake phase with fast acquisitions in addition to providing high resolution peak- and post-contrast images. A good correlation between the results based on the maximum slope of the signal enhancement in the initial phase and that based on the standard protocol was found, indicating a potential of shortening the breast MRI scan time and in turn a lowering of the breast MRI cost with this new technique.

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