Abstract #3880
Assessment of the correlation between ADC values and Oncotype DX score in estrogen-receptor positive, lymph node negative, breast cancers
Sunitha B Thakur 1 , Manuela Durando 2 , Milans Soledad 3 , Elizabeth J Sutton 2 , Dilip Giri 2 , and Elizabeth A Morris 2
1
Memorial Sloan Kettering Cancer Center, New
York, NY, United States,
2
Memorial
Sloan Kettering Cancer Center, NY, United States,
3
Memorial
Sloan Kettering Cancer Center, New YORK, NY, United
States
Preliminary studies have attempted to evaluate Apparent
Diffusion Coefficient (ADC) values for its potential
prognostic utility. However the impact of ADC on
prognosis remains to be clearly defined. This study was
conducted with the goal of determining whether there
exists a correlation between ADC values and Oncotype Dx
scores in estrogen-receptor positive and lymph node
negative breast cancers. We found that mean ADC values
were higher in Oncotype DX score stratified low risk
cancers than in intermediate risk cancers. Our data at
3.0T MRI suggests that lower ADC values correlate with a
higher Oncotype DX score and consequently, an increased
risk of recurrence.
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