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Abstract #3883

Registration of Multiparametic Breast MRI

Lawrence Kenning 1 , Martin Pickles 1 , and Lindsay Turnbull 1

1 Centre for MR Investigations, Hull York Medical School at University of Hull, Hull, United Kingdom

Motion during breast MR examination can degrade DCE data and cause spatial mismatches between sequences. Data acquired from 19 patients was retrospectively corrected using rigid and non-rigid schemes. For the DCE series, mean coefficients of variation were found to be 45.23.9%, 40.03.1% and 35.72.5% for the original data, rigid motion corrected data and the non-rigid motion corrected data. Non-rigid registration between MR series was successfully applied to all patients and showed good visual agreement. The global 4D registration methodology enables researchers and clinicians to contour single volume of interests that can be used to simultaneously interrogate multiple breast MR series.

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