Abstract #3897
DCE-MRI of prostate cancer: perfusion quantification with Tofts model vs. shutter-speed model. Initial experience.
Cecilia Besa 1 , Guido Jajamovich 2 , Adnan Ali 3 , Wei Huang 4 , Kenneth Haines 5 , Ash Tewari 3 , and Bachir Taouli 6
1
Radiology, Icahn School of Medicine at Mount
Sinai, New York, NY, United States,
2
icahn
School of Medicine at Mount Sinai, NY, United States,
3
Urology,
Icahn School of Medicine at Mount Sinai, NY, United
States,
4
Radiology,
Oregon Health & Science University, Portland, OR, United
States,
5
Pathology,
Icahn School of Medicine at Mount Sinai, NY, United
States,
6
Icahn
School of Medicine at Mount Sinai, New York, NY, United
States
Synopsis: The purpose of this study was to evaluate the
value of quantitative diffusion weighted imaging (DWI)
and dynamic contrast enhanced (CE) MRI in predicting
histopathologic characteristics of liver metastatic
neuroendocrine tumors (NET). We found that
neuroendocrine carcinoma (G3) liver metastases had
significantly lower ADC values and higher arterial
enhancement rate (ER) than Grade 1 and 2 NETs. In
addition, significant negative correlation was observed
between ADC and ER and mitotic count and Ki-67% labeling
index. DWI with ADC quantification and CE-MRI may be
useful for predicting tumor grade in metastatic hepatic
NET.
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