Abstract #3898
The Effect of Groupwise Elastic Registration in Discrimination of Benign and Malignant Ovarian Cancers by Pharmacokinetic Parameters
Elaheh Kia 1,2 , Anahita Fathi Kazerooni 1,2 , Saeedeh Navaei Lavasani 1,2 , Alireza Ahmadian 2 , and Hamidreza Saligheh Rad 1,2
1
Quantitative MR Imaging and Spectroscopy
Group, Research Center for Molecular and Cellular
Imaging, Tehran University of Medical Sciences, Tehran,
Iran,
2
Department of Medical Physics and
Biomedical Engineering, School of Medicine, Tehran
University of Medical Sciences, Tehran, Iran
Dynamic contrast enhanced MRI (DCE-MRI) has shown to be
promising for quantitative assessment of complex ovarian
cancers. Quantification of DCE-MR images could be
affected by motion artifacts and intensity inhomogeneity
induced by bias fields. Proper selection of a
registration algorithm could impact the outcome of this
problem. In this work, we proposed an efficient
non-rigid registration method in a group-wise setting to
non-rigidly align DCE-MR images to reliable
quantification of ovarian masses.
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