Quantification of changes in resting state connectivity in monkey SI cortex following spinal cord injury

Spinal cord is primarily responsible for transmitting sensory and motor information to and from the brain. Disruptions following injury on the spinal cord affect the functional integrity of somatic sensory networks. This study aims to determine whether the disruption of afferent inputs from the cervical spinal cord alter the fine - scale functional connectivity between sub-regions of SI cortex in the resting state. We performed an ROI based analysis of resting state BOLD MRI signals obtained in pre- versus post- lesion conditions in anesthetized squirrel monkeys at 9.4T to quantify the inter-regional functional connectivity differences between the sub-regions of the SI cortex.

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