Meeting Banner
Abstract #3903

Deep Anesthesia Provokes Dissimilar Resting State Connectivities in ADHD Rat Model and Normal Control

Sheng-Min Huang 1 , Wei-Cheng Lee 1 , Kung-Chu Ho 2 , and Fu-Nien Wang 1

1 Department of Biomedical Engineering & Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, 2 Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan

In this abstract the resistance to isoflurane anesthesia between ADHD model (SHR) and normal control (WKY) was compared by using resting state functional MRI. A different distribution of remaining network under high dose anesthesia was found. WKY group tends to preserve the frontal region of brain, while SHR group keep the central region. Since we can speculate that the connections in high anesthesia level are very fundamental networks, these basic differences between SHR and WKY may be one of the origins of functional abnormality in ADHD rat.

This abstract and the presentation materials are available to members only; a login is required.

Join Here