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Abstract #3916

Acceleration of task-based FMRI using k-t FASTER

Mark Chiew 1 , Nadine N Graedel 1 , Stephen M Smith 1 , and Karla L Miller 1

1 FMRIB Centre, University of Oxford, Oxford, Oxfordshire, United Kingdom

We demonstrate application of k-t FASTER, a low-rank acceleration technique designed for FMRI data, on visual task FMRI data acquisition. Here, we used a 3D hybrid radial-Cartesian sampling strategy with combined parallel imaging to acquire 2 mm isotropic whole brain BOLD-weighted images at 0.6 s temporal resolution. Our results show that k-t FASTER at high accelerations is capable of capturing task-related FMRI activation with high sensitivity, and that an independent components analysis of the principal component subspace directly estimated by k-t FASTER reproduces the expected temporal and spatial patterns elicited by the visual task with high fidelity.

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