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Abstract #3917

Demonstration of recovery of signal loss at 7T in Gradient Echo EPI using Tailored-RF pulses

Catarina Rua 1 , Stephen James Wastling 2 , Mauro Costagli 3 , Laura Biagi 4 , Mark Roger Symms 5 , Alberto del Guerra 1 , Mirco Cosottini 1,3 , Michela Tosetti 3,4 , and Gareth John Barker 2

1 University of Pisa, Pisa, Italy, 2 Neuroimaging, King's College London, London, United Kingdom, 3 IMAGO7 Foundation, Pisa, Italy, 4 IRCCS Stella Maris, Pisa, Italy, 5 GE Healthcare, Pisa, Italy

We show that signal losses associated with slice selective excitation in Gradient Echo (GE) EPI at 7T can be recovered by the use of specially designed Tailored-RF (TRF) pulses. Three subjects were tested with both a standard GE sequence and a TRF modified GE-EPI pulse sequence at three different resolutions. Also, a spin-echo EPI was taken in one of the subjects for comparison. It was possible to observe signal recovery in lower temporal lobe regions in the TRF sequence even with an expected global SNR drop. This work shows a potential applicability for functional brain imaging in lower brain regions.

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