Demonstration of recovery of signal loss at 7T in Gradient Echo EPI using Tailored-RF pulses
Catarina Rua 1 , Stephen James Wastling 2 , Mauro Costagli 3 , Laura Biagi 4 , Mark Roger Symms 5 , Alberto del Guerra 1 , Mirco Cosottini 1,3 , Michela Tosetti 3,4 , and Gareth John Barker 2
University of Pisa, Pisa, Italy,
King's College London, London, United Kingdom,
Foundation, Pisa, Italy,
Stella Maris, Pisa, Italy,
We show that signal losses associated with slice
selective excitation in Gradient Echo (GE) EPI at 7T can
be recovered by the use of specially designed
Tailored-RF (TRF) pulses. Three subjects were tested
with both a standard GE sequence and a TRF modified
GE-EPI pulse sequence at three different resolutions.
Also, a spin-echo EPI was taken in one of the subjects
for comparison. It was possible to observe signal
recovery in lower temporal lobe regions in the TRF
sequence even with an expected global SNR drop. This
work shows a potential applicability for functional
brain imaging in lower brain regions.
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