Abstract #3958
Wavelet Coherence Analysis of Functional Connectivity within Default Mode Network Employing Simultaneous MultiSlice (SMS) Resting-state fMRI
Hesamoddin Jahanian 1 , Samantha Holdsworth 1 , Thomas Christen 1 , Hua Wu 2 , Kangrong Zhu 3 , Adam Kerr 3 , Mathew J Middione 4 , Robert F Dougherty 2 , Michael Moseley 1 , and Greg Zaharchuk 1
1
Department of Radiology, Stanford
University, Stanford, CA, United States,
2
Center
for Cognitive and Neurobiological Imaging, Stanford
University, Stanford, CA, United States,
3
Department
of Electrical Engineering, Stanford University,
Stanford, CA, United States,
4
Applied
Sciences Laboratory West, GE Healthcare, Menlo Park, CA,
United States
In this work we studied the dynamics of functional
connectivity within the default mode network using high
temporal sampling rate (TR=350 ms) Simultaneous
MultiSlice (SMS) Resting-state fMRI. We performed
wavelet coherence analysis in two frequency bands:
0.01-0.1 Hz and above 0.1 Hz. Our results indicate that
functional connectivity occurs at multiple frequency
bands including those above 0.1 Hz that are commonly
ignored in rsfMRI studies and exhibits dynamic changes
within time scales of seconds to minutes.
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