Comparison Between Whole-Body Coronal and Axial DWI Performed During PET-MR

As the plane of acquisition in MRI can alter image quality and lesion detectability, we evaluated the preferred acquisition plane for diffusion-weighted imaging (DWI) acquired as a component of whole body PET-MR examinations. Two readers evaluated DWI images from PET-MR data sets acquired in coronal (cDWI) and axial (aDWI) planes. Ability to identify lesions was compared to PET-CT; both cDWI and aDWI demonstrated good sensitivity, however, specificity on a by-patient basis was low due to false positive findings in osseous structures and lymph nodes. Readers demonstrated less uncertainty regarding findings and rated image quality higher on cDWI images.

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