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Abstract #4007

The value of Gd-EOB-DTPA enhanced MR imaging in characterizing cirrhotic nodules with atypical enhancement in Gd-DTPA enhanced MRI imaging

Yi-Chun Wang 1,2 , Wen-Pei Wu 2,3 , Cheng-In Hoi 2 , Chen-Te Chou 2,3 , and Ran-Chou Chen 2,4

1 Radiology, taoyuan general hospital ministry of health and welfare, Taiwan, Taoyuan, Taiwan, 2 Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan, 3 Radiology, Chang-Hua Christian Hospital, Taiwan, 4 Radiology, Taipei city Hospital, Taiwan, Taipei, Taiwan

According to AASLD, a diagnosis of HCC can be made by that a nodule larger than 1.0 cm showed typical enhancement on dynamic CT or MR. However, up to 44% HCCs show atypical features on dynamic contrast-enhanced images. The purpose of this study was to evaluate whether Gd-EOB-DTPA enhanced hepatocyte phase MR images can improve the diagnosis of HCC in patients with atypical enhanced cirrhotic nodules detected on conventional dynamic MR images. In our study, hypointense on hepatocyte phase having 83.5% diagnostic accuracy is superior to the dynamic phases. If we combine the hypointensity on hepatocyte phase with arterial hypervascularity, the specificity will be 95.7%. However, when we combined the hypointensity on hepatocyte phase with arterial isovascularity, the specificity is only 73.9%.

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