Abstract #4040
Introvoxel incoherent motion (IVIM) with multi-b values DWI in the diagnosis and grading of cervical cancer
Yan Zhou 1 , Jianyu Liu 2 , Wei He 2 , Yang Shen 2 , Weidan Lu 2 , Huici Zhu 2 , Dandan Zheng 3 , and Ziheng Zhang 3
1
Peking University Third Hospital, Beijing,
Beijing, China,
2
Peking
University Third Hospital, Beijing, China,
3
GE
Healthcare, Beijing, China
This study aimed at investigating the utility of intra-voxel
incoherent motion model (IVIM) with multi-b values DWI
in diagnosis and grading of cervical cancer. Moreover,
the up to date concept of invasive edge of tumor was
adopted, which had closer relation with tumor
aggressiveness and prognosis. The results showed that
both mono-exponential model and IVIM model could help to
differentiate cervical cancer from normal cervix.
Perfusion fraction (F) at tumor edge showed the best
diagnostic performance in grading cervical squmous
cancer. Therefore, IVIM model might demonstrate
capability on differentiating and grading cervical
cancer.
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