Abstract #4062
Multivoxel Proton Magnetic Resonance Spectroscopy for Non-Invasive Thermometry: Improvements in Spectral Quality using semiLASER with GRE Shim
Candace C. Fleischer 1,2 , Deqiang Qiu 3 , Xiaodong Zhong 4 , Hui Mao 3 , John N. Oshinksi 3 , Xiaoping Hu 1,2 , and Seena Dehkharghani 3
1
Biomedical Imaging Technology Center, Emory
University, Atlanta, GA, United States,
2
Biomedical
Engineering, Emory University, Atlanta, GA, United
States,
3
Radiology
and Imaging Sciences, Emory University Hospital,
Atlanta, GA, United States,
4
MR
R&D Collaborations, Siemens Healthcare, Atlanta, GA,
United States
Current brain thermometry methods are costly and highly
invasive. Chemical shift imaging (CSI) is a promising
technique for non-invasive thermometry utilizing
temperature-dependent chemical shift differences between
water and N-acetylaspartate. The current standard using
a PRESS sequence with automated shimming suffers from
poor spatial resolution and chemical shift artifacts. We
present a CSI protocol for thermometry with quantitative
improvements to shimming and spectral quality in vitro
and in vivo: a semiLASER spectroscopy sequence with GRE
Shim. Combining the semiLASER advanced voxel
localization with a more homogenous magnetic field from
GRE Shim will be beneficial for thermometry and other
applications of CSI.
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