Abstract #4079
Liver Iron Content Determination using GRE and Signal Intensity Ratio Analysis in MR Systems from Different Vendors
Arthur Peter Wunderlich 1,2 , Meinrad Beer 1 , Peter Bernhardt 3 , Holger Cario 4 , Vinzenz Hombach 3 , Reinhard Meier 1 , Wolfgang Rottbauer 3 , Stefan Andreas Schmidt 1 , and Volker Rasche 3
1
Clinic for Diagnostic and Interventional
Radiology, Univ.-Clinic Ulm, Ulm, Germany,
2
Section
for Experimental Radiology, Univ.-Clinic Ulm, Ulm,
Germany,
3
Clinic for Internal Medicine II -
Cardiology, Univ.-Clinic Ulm, Ulm, Germany,
4
Clinic
for Pediatrics, Univ.-Clinic Ulm, Ulm, Germany
Since existing methods for determining Liver Iron
Content (LIC) are based on Signal Intensity Ratio (SIR),
we studied compatibility of SIR values between scanners
from different vendors. Patients suspected for liver
iron overload were examined at two different scanners
the same day at 1.5 T. SIR values of in-phase GRE images
calculated from three liver ROIs and two in paraspinal
muscles, and LIC calculated using SIR obtained from both
scanners were compared by statistical methods. SIR
values showed good correlation but didnt match
properly. However, calculated LIC values were in good
agreement between scanners, especially when working with
RF spoiling.
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