Measuring the unsaturation index in red and yellow bone marrow using 1 H MR spectroscopy
Alessandra Bierwagen 1,2 , Bettina Nowotny 1,2 , Julia Szendroedi 1,3 , Karsten Mssig 1,3 , Michael Roden 1,3 , and Jesper Lundbom 1,2
Institute for Clinical Diabetology, German
Diabetes Center, Leibniz Institute for Diabetes
Research, Heinrich Heine University, Duesseldorf,
Center for Diabetes Research (DZD e.V.), Partner
Dsseldorf, Duesseldorf, Germany,
of Endocrinology and Diabetology, University Hospital
This study compared intrasubject changes in lipid
unsaturation in yellow and red bone marrow and
correlated these parameters to physical activity, age
and BMI. Long-TE
MRS spectra were acquired in the bone marrow of the
femur of 9 female subjects. The mean unsaturation index
of the red bone marrow was significantly lower than the
unsaturation index of yellow bone marrow. RBM
unsaturation correlated with the BAECKE sport index.
Furthermore the fat content of the red bone marrow
correlated with age.
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