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Abstract #4085

Magnetic Resonance Spectroscopy of Breast Cancer using the SLIM Technique Initial Results

Patrick J Bolan 1,2 , Steen Moeller 1 , Gregory J Metzger 1,2 , Michael Garwood 1,2 , Douglas Yee 2,3 , and Michael T Nelson 1,2

1 Radiology, University of Minnesota, Minneapolis, MN, United States, 2 Masonic Cancer Center, University of Minnesota, Minneapolis, MN, United States, 3 Medicine, University of Minnesota, Minneapolis, MN, United States

Magnetic resonance spectroscopy (MRS) can provide clinically valuable metabolic information for diagnosing and treating breast cancer, but current acquisition techniques need improvement. Single-voxel MRS (SVS) gives good quality but requires expertise to acquire, whereas chemical shift imaging (CSI) methods are easier to acquire but give lower quality spectra. Our long-term goal is to use a technique known as Spectral Localization by IMaging (SLIM) to reconstruct acquired CSI data, producing high-quality spectra comparable to SVS but with the robust acquisition of CSI. This work presents initial results in breast cancer showing SLIM spectra that are comparable or better than CSI.

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