Abstract #4086
Investigation of 3D Lava-flex in fat fraction estimation for patients with hepatic iron-overloading
Tianyong Xu 1 , Qian Jiang 1 , Bing Wu 1 , Kai Xu 2 , and Zhenyu Zhou 1
1
GE Healthcare China, Beijing, Beijing,
China,
2
The
Affiliated Hospital of Xuzhou Medical College, Xuzhou,
Jiangsu, China
Knowledge of fat content in liver is not only useful for
hepatic disease diagnosis but also valuable in
monitoring recovery and assessing treatment
effectiveness. Dual echo 2D SPGR is a routinely used
sequence for obtaining the quantitative fat fraction by
deriving the signal intensity ratios of in-phase and
out-of-phase images. However it may fail for patients
with liver iron-overloading that leads to shortened T2*,
and the in-phase images suffer from low SNR that affects
the accuracy of calculation. We investigate if the
LAVA-flex sequence may be an iron overloading immune
method for fat fraction assessment in patients diagnosed
with hematopathy.
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