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Abstract #4091

Postprandial changes of secretory flow of pancreatic juice in the main pancreatic duct: Evaluation with cine dynamic MRCP and a spatially selective inversion recovery (IR) pulse

Kazuya Yasokawa 1 , Akira Yamamoto 1 , Tsutomu Tamada 1 , Akihiko Kanki 1 , Atsushi Higaki 1 , Yasufumi Noda 1 , and Katsuyoshi Ito 1

1 Radiology, Kawasaki Medical School, Kurashiki, Okayama, Japan

This study evaluated the influence of oral ingestion in secretory flow dynamics of physiological pancreatic juice within the main pancreatic duct in 38 healthy volunteers by using cine-dynamic MRCP and a spatially selective IR pulse non-invasively. The median secretion grade of pancreatic juice at 5-19 minutes after ingestion was significantly higher than that before ingestion. Secretion grade of pancreatic juice showed a maximum peak at 19 minutes after ingestion, and then, began to gradually decline, compared with that of maximum peak value. This technique may have a potential to evaluate physiological pancreatic exocrine function in postprandial state.

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