Abstract #4095
Characterize Hepatocellular Carcinoma with IVIM-DWI and DCE-MRI in Combination: Preliminary Experience
Lifen Xie 1,2 , Changhong Liang 1 , Zaiyi Liu 1 , Queenie Chan 3 , and Yingjie Mei 4
1
Department of Radiology, Guangdong Academy
of Medical Sciences/Guangdong General Hospital,
Guangzhou, Guangdong, China,
2
Southern
Medical University, Guangzhou, Guangdong, China,
3
Philips
Healthcare, HK, China,
4
Philips
Healthcare, Guangzhou, Guangdong, China
To quantify diffusion and perfusion characteristics of
hepatocellular carcinoma (HCC) with both IVIM and DCE
MRI, and to evaluate the correlation between the
resulting parameters. 35 patients with cirrhosis and
HCCs underwent IVIM and DCE-MRI scans. DCE-MRI
parameters (Ktrans, kep, ve and vp) and IVIM parameters
(D,D* and f) were obtained. The correlation between
IVIM-DWI and DCE-MRI parameters of HCCs, and differences
of IVIM-DWI parameters between liver parenchyma and HCCs
were analyzed Paired-Samples T Test or Wilcoxon Test.
The results demonstrated vp was inversely correlated
with D in HCCs, and HCCs showed significantly lower ADC,
D, f and D* values compared to liver parenchyma
(P0.001). IVIM-DWI provides parameters that are
significantly different in HCC compared to liver
parenchyma.
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