Abstract #4149
Near Infrared Optical Tomography at MR resolution: Photo-magnetic Imaging
Alex Luk 1 , Yuting Lin 2 , David Thayer 3 , Seunghoon Ha 4 , and Gultekin Gulsen 1
1
UC Irvine, Irvine, California, United
States,
2
Harvard
Medical School, Massachusetts, United States,
3
UC
Irvine Medical, Irvine, California, United States,
4
UC
Irvine, Irvine, california, United States
Diffuse optical imaging is advantageous in enhancing
tumor diagnosis by providing functional information but
suffers from low resolution. We combined MR thermometry
and diffuse optical tomography and built the first
prototype photo magnetic imaging system. It provides
in-vivo functional information with MR resolution and
helps to monitor different optical contrast agents such
as Indocyanine green. A finite element based forward
simulation of the laser induced temperature change map
has been compared with PMI measurements. The forward
simulation accurately estimates the temperature
tomography collected by MR thermometry. By solving the
inverse problem with multiple wavelengths, we will be
able to reconstruct MR resolution tomography of
different chromophores concentrations.
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