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Abstract #4163

10 minute isotropic MRI of the knee using accelerated 3D SPACE with incoherent undersampling and iterative reconstruction: Comparison with standard 2D TSE MRI

Jan Fritz 1 , Gaurav Thawait 1 , Shivani Ahlawat 1 , Shadpour Demehri 1 , Heiko Meyer 2 , Wesley Gilson 3 , and Esther Raithel 2

1 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, 2 Healthcare Sector, Siemens AG, Erlangen, Bavaria, Germany, 3 Siemens Healthcare USA, Baltimore, MD, United States

While high spatial resolution, isotropic 3D MRI of knee can achieve similar diagnostic performance than standard 2D MRI, the acquisition of 3D data can be time-consuming and may conflict with its practicability. K-space undersampling and iterative reconstruction is a method that can yield substantial acceleration of 3D data acquisition. In this study, we show how the implementation of k-space undersampling and iterative reconstruction into a SPACE pulse sequence prototype enables accelerated, comprehensive, high-spatial-resolution 3D MRI of the knee in under 10 min with image qualities that rivals standard 2D TSE images and potential to replace a more time-consuming 20 min standard 2D TSE MRI protocol.

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