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Abstract #4162

Four-fold reduction in scan time for skeletal age examination enabled by adaptive compressed sensing MRI

Yasuhiko Terada 1 , Keiichiro Ishi 1 , Daiki Tamada 1 , Katsumi Kose 1 , Taiki Nozaki 2 , Yasuhito Kaneko 2 , Ryo Miyagi 2 , and Hiroshi Yoshioka 2

1 Institue of Applied Physics, University of Tsukuba, Tsukuba, Ibaraki, Japan, 2 Department of Radiological Sciences, University of California Irvine, Irvine, CA, United States

Skeletal age of a young child is assessed by rating the maturity stage of left-hand bones in the MRI images. We have used a 0.3 T open scanner to provide a comfortable examination environment for children, and showed the validity of the skeletal age examination. However, the long scan times for 3D imaging are uncomfortable for children and often induce motion artifacts in the images. In the previous study, we used compressed sensing (CS) to shorten the long scan time, but the acceleration factor (AF) was limited to 2 because of the low signal-to-noise ratio. To further decrease the scan time, it is necessary to optimize the CS sampling pattern for skeletal age examination with knowledge of the nature of data to be reconstructed. In this study, we optimize the sampling pattern using the database of hand images obtained in the previous study and realize the 40-second scan (AF = 4). Both the simulation and experimental results reveal the validity of the CS-based skeletal examination using optimal sampling.

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