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Abstract #4161

Time efficient and quantitative Sodium imaging at 7T using compressed sensing accelerated FID spectroscopic imaging

Jetse van Gorp 1 , Paul de Bruin 2 , and Peter Seevinck 1

1 Image Sciences Institute, University Medical Center Utrecht, Utrecht, Utrecht, Netherlands, 2 Department of Radiology, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands

In this work we propose a flexible and quantitative method for sodium (23Na) imaging to determine the total sodium concentration (TSC) and characterize the signal decay, which is related to bound and unbound 23Na. A (compressed sensing accelerated) 3D FID spectroscopic imaging sequence is used to maximize the ratio between sampling time and total acquisition time to optimize the SNR, obtain a high temporal resolution and acquire 23Na images in both a calibration phantom and in the knee of a healthy volunteer.

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